Synthetic methyl hexagalacturonate hapten inhibitors of antihomogalacturonan monoclonal antibodies LM7, JIM5 and JIM7

Mads Hartvig Clausen, William George Tycho Willats, J. Paul Knox

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

A range of synthetic methyl hexagalacturonates were used as potential hapten inhibitors in competitive-inhibition enzyme-linked immunosorbent assays (ELISAs) with anti-homogalacturonan monoclonal antibodies LM7, JIM5 and JIM7. The selective inhibition of these antibodies by different haptens provides insight into the structures of the partially methyl-esterified pectin epitopes of these widely used monoclonal antibodies.
Original languageEnglish
JournalCarbohydrate Research
Volume338
Issue number17
Pages (from-to)1797-1800
ISSN0008-6215
DOIs
Publication statusPublished - 2003

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