Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline

Niels Grøn Nørager, Linda Luise Reeh Lorentz-Petersen, Lars Ole Lyngsø, Jan Kehler, Karsten Juhl

Research output: Contribution to journalLetterpeer-review

Abstract

A versatile procedure for the synthesis of optically pure 1-amino-3-aryl indanes is presented, exemplified by the synthesis of the triple uptake inhibitor (+)-indatraline (1).
Original languageEnglish
JournalSYNLETT: Accounts and Rapid Communications in Chemical Synthesis
Issue number12
Pages (from-to)1753-1755
ISSN0936-5214
DOIs
Publication statusPublished - 2011

Keywords

  • Conjugate addition
  • Rhodium
  • Indatraline
  • Enzymatic resolution
  • Indane

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