Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline

Niels Grøn Nørager; Linda Luise Reeh Lorentz-Petersen; Lars Ole Lyngsø; Jan Kehler; Karsten Juhl

doi:10.1055/s-0030-1260823

Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline

Niels Grøn Nørager, Linda Luise Reeh Lorentz-Petersen, Lars Ole Lyngsø, Jan Kehler, Karsten Juhl

Department of Chemistry

Research output: Contribution to journal › Letter › peer-review

Abstract

A versatile procedure for the synthesis of optically pure 1-amino-3-aryl indanes is presented, exemplified by the synthesis of the triple uptake inhibitor (+)-indatraline (1).

Original language	English
Journal	SYNLETT: Accounts and Rapid Communications in Chemical Synthesis
Issue number	12
Pages (from-to)	1753-1755
ISSN	0936-5214
DOIs	https://doi.org/10.1055/s-0030-1260823
Publication status	Published - 2011

Keywords

Conjugate addition
Rhodium
Indatraline
Enzymatic resolution
Indane

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title = "Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline",

abstract = "A versatile procedure for the synthesis of optically pure 1-amino-3-aryl indanes is presented, exemplified by the synthesis of the triple uptake inhibitor (+)-indatraline (1).",

keywords = "Conjugate addition, Rhodium, Indatraline, Enzymatic resolution, Indane",

author = "N{\o}rager, {Niels Gr{\o}n} and Lorentz-Petersen, {Linda Luise Reeh} and Lyngs{\o}, {Lars Ole} and Jan Kehler and Karsten Juhl",

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language = "English",

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T1 - Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline

AU - Nørager, Niels Grøn

AU - Lorentz-Petersen, Linda Luise Reeh

AU - Lyngsø, Lars Ole

AU - Kehler, Jan

AU - Juhl, Karsten

PY - 2011

Y1 - 2011

N2 - A versatile procedure for the synthesis of optically pure 1-amino-3-aryl indanes is presented, exemplified by the synthesis of the triple uptake inhibitor (+)-indatraline (1).

AB - A versatile procedure for the synthesis of optically pure 1-amino-3-aryl indanes is presented, exemplified by the synthesis of the triple uptake inhibitor (+)-indatraline (1).

KW - Conjugate addition

KW - Rhodium

KW - Indatraline

KW - Enzymatic resolution

KW - Indane

U2 - 10.1055/s-0030-1260823

DO - 10.1055/s-0030-1260823

M3 - Letter

SN - 0936-5214

SP - 1753

EP - 1755

JO - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

JF - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

IS - 12

ER -

Synthesis of Optically Pure 1-Amino-3-aryl Indanes Exemplified by (+)-Indatraline

Abstract

Keywords

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