Synthesis of graphene quantum dots and their applications in drug delivery

Changhong Zhao*, Xuebin Song, Ya Liu, Yifeng Fu, Lilei Ye, Nan Wang, Fan Wang, Lu Li, Mohsen Mohammadniaei, Ming Zhang, Qiqing Zhang, Johan Liu

*Corresponding author for this work

Research output: Contribution to journalReviewResearchpeer-review

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Abstract

This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.[Figure not available: see fulltext.]
Original languageEnglish
Article number142
JournalJournal of Nanobiotechnology
Volume18
Issue number1
Number of pages32
ISSN1477-3155
DOIs
Publication statusPublished - 2020

Keywords

  • Graphene quantum dots
  • Top-down
  • Bottom-up
  • Drug delivery
  • Delivery-release mode

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