Abstract
Using the cis-fused cyclopentane-1,4-lactone,
1(R),5(S)-7(R),8(R)-dihydroxy-2-oxabicyclo[3.3.0]oct-3-one (1), as
starting material, 5-deoxycarba-*-L-xylo-hexofuranose (6) together
with ?- (12) and ?-1-amino-1,5-dideoxycarba-L-xylo-hexofuranose
(16) have been prepared using a number of stereoselective
transformations. The key step was the regioselective opening of
the epoxide 1(R),5(S)-7(R),8(R)-epoxy-2-oxabicyclo[3.3.0]oct-3-one
(4) with different nucleophiles.
| Original language | English |
|---|---|
| Journal | Synthesis |
| Pages (from-to) | 171-177 |
| Publication status | Published - 1999 |