Synthesis of 3-C-hydroxymethyl- and 3-deoxyisofagomine and investigation of their binding to β-glucosidase

Henrik Hallberg Jensen, Anders Lohse, Bent O. Petersen, Jens Øllgaard Duus, Mikael Bols

Research output: Contribution to journalJournal articleResearchpeer-review


The synthesis of 3-C-hydroxymethyl- and 3-deoxyisofagomine was presented. The reactions were performed under an inert atmosphere in preheated glass equipments. The results showed that the binding of 3-deoxy-compound was increased by introducing hydroxy group in isofagomine.
Original languageEnglish
JournalRoyal Chemical Society. Journal. Perkin Transactions 2
Issue number5
Pages (from-to)667-670
Publication statusPublished - 2000
Externally publishedYes


  • Biochemistry
  • Catalysis
  • Hydrogenation
  • Nuclear magnetic resonance spectroscopy
  • Stereochemistry
  • Synthesis (chemical)
  • Organic compounds
  • X
  • Biochemical tools

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