Synthesis and characterization of ratiometric nanosensors for pH quantification: a mixed micelle approach

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    Abstract

    Optical nanoparticle pH sensors designed for ratiometric measurements have previously been synthesized using post-functionalization approaches to introduce sensor molecules and to modify nanoparticle surface chemistry. This strategy often results in low control of the nanoparticle surface chemistry and is prone to batch-to-batch variations, which is undesirable for succeeding sensor calibrations and cellular measurements. Here we provide a new synthetic approach for preparing nanoparticle pH sensors based on self-organization principles, which in comparison to earlier strategies offers a much higher design flexibility and high control of particle size, morphology and surface chemistry.
    Original languageEnglish
    JournalChemical Communications
    Volume48
    Issue number39
    Pages (from-to)4776-4778
    ISSN1359-7345
    DOIs
    Publication statusPublished - 2012

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