Synergistic Activities of an Efflux Pump Inhibitor and Iron Chelators against Pseudomonas aeruginosa Growth and Biofilm Formation

Yang Liu, Liang Yang, Søren Molin

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The efflux pump inhibitor phenyl-arginine-beta-naphthylamide (PA beta N) was paired with iron chelators 2,2'-dipyridyl, acetohydroxamic acid, and EDTA to assess synergistic activities against Pseudomonas aeruginosa growth and biofilm formation. All of the tested iron chelators synergistically inhibited P. aeruginosa growth and biofilm formation with PA beta N. PA beta N-EDTA showed the most promising activity against P. aeruginosa growth and biofilm formation.
    Original languageEnglish
    JournalAntimicrobial Agents and Chemotherapy
    Volume54
    Issue number9
    Pages (from-to)3960-3963
    ISSN0066-4804
    DOIs
    Publication statusPublished - 2010

    Fingerprint Dive into the research topics of 'Synergistic Activities of an Efflux Pump Inhibitor and Iron Chelators against Pseudomonas aeruginosa Growth and Biofilm Formation'. Together they form a unique fingerprint.

    Cite this