Suspected zoonotic transmission of rotavirus group A in Danish adults

S. E. Midgley, Charlotte Kristiane Hjulsager, Lars Erik Larsen, G. Falkenhorst, B. Böttiger

    Research output: Contribution to journalJournal articleResearchpeer-review

    465 Downloads (Pure)

    Abstract

    Group A rotaviruses infect humans and a variety of animals. In July 2006 a rare rotavirus strain with G8P[14] specificity was identified in the stool samples of two adult patients with diarrheoa, who lived in the same geographical area in Denmark. Nucleotide sequences of the VP7, VP4, VP6, and NSP4 genes of the identified strains were identical. Phylogenetic analyses showed that both Danish G8P[14] strains clustered with rotaviruses of animal, mainly, bovine and caprine, origin. The high genetic relatedness to animal rotaviruses and the atypical epidemiological features suggest that these human G8P[14] strains were acquired through direct zoonotic transmission events.
    Original languageEnglish
    JournalEpidemiology and Infection
    Volume140
    Issue number6
    Pages (from-to)1013–1017
    ISSN0950-2688
    DOIs
    Publication statusPublished - 2012

    Bibliographical note

    PMID: 21943834.

    Keywords

    • Rotavirus
    • Zoonoses

    Cite this

    Midgley, S. E., Hjulsager, C. K., Larsen, L. E., Falkenhorst, G., & Böttiger, B. (2012). Suspected zoonotic transmission of rotavirus group A in Danish adults. Epidemiology and Infection, 140(6), 1013–1017. https://doi.org/10.1017/S0950268811001981