Susceptibility of Muscovy (Cairina Moschata) and mallard ducks (Anas Platyrhynchos) to experimental infections by different genotypes of H5N1 avian influenza viruses

Do Quy Phuong, Nguyen Tien Dung, Poul Henrik Jørgensen, Kurt Jensen Handberg, Nguyen The Vinh, Jens Peter Christensen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    It is a fact that in Viet Nam, Muscovy ducks are raised in large populations (approximately 8 million), usually kept in small flocks together with mallards and chickens. As a result, it is a great concern for epidemiologists to elucidate possible differences in relation to these species being exposed to infection with H5N1. To do this, an experimental study on infections with different genotypes of H5N1 in mallards and Muscovy ducks have been conducted, where it was found that the mortality of the inoculated Muscovy ducks was at least 80%, regardless of the virus strain employed. In contrast, the mortality of the mallards ranged from nil to 100%, which suggests that Muscovy ducks are more susceptible to HPAIV H5N1 infection in terms of disease development and mortality. It was also found that higher virus titers developed in vital organs of Muscovy ducks compared to mallards, particularly in the brain. Due to their high susceptibility, it is unlikely that Muscovy ducks act as a silent reservoir. The virus strains used in this study, to a certain degree, differed in their virulence properties to the bird species in question.
    Original languageEnglish
    JournalVeterinary Microbiology
    Volume148
    Issue number2-4
    Pages (from-to)168-174
    ISSN0378-1135
    DOIs
    Publication statusPublished - 2011

    Keywords

    • Experimental infection
    • Ducks
    • Muscovy ducks
    • Avian influenza
    • H5N1
    • Mallard ducks

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