Susceptibility of Clostridium difficile Toward Antimicrobial Agents Used as Feed Additives for Food Animals

Frank Møller Aarestrup; Michael Tvede

doi:10.1089/mdr.2010.0068

Susceptibility of Clostridium difficile Toward Antimicrobial Agents Used as Feed Additives for Food Animals

Frank Møller Aarestrup, Michael Tvede

National Food Institute

Copenhagen University Hospital Herlev and Gentofte

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Abstract

A total of 65 toxigenic Clostridium difficile strains isolated from patients with antibiotic-associated diarrhea were tested for susceptibility to avilamycin, flavomycin, monensin, and salinomycin. Except for flavomycin the substances showed in vitro efficacy comparable to reports of the currently most commonly used drugs for treatment of C. difficile. This indicates that these old compounds may be useful for the treatment of C. difficile infections in man and perhaps for other bacterial causes of diarrhea.

Original language	English
Journal	Microbial Drug Resistance
Volume	17
Issue number	1
Pages (from-to)	125-127
ISSN	1076-6294
DOIs	https://doi.org/10.1089/mdr.2010.0068
Publication status	Published - 2011

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Susceptibility of Clostridium difficile Toward Antimicrobial Agents Used as Feed Additives for Food Animals

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