45Ti extraction using hydroxamate resin

K. Gagnon, Gregory Severin, T. E. Barnhart, J. W. Engle, H. F. Valdovinos, R. J. Nickles

    Research output: Contribution to journalConference articleResearchpeer-review

    Abstract

    As an attractive radionuclide for positron emission tomography, this study explores the extraction and reactivity of 45Ti produced via the 45Sc(p,n)45Ti reaction on a GE PETtrace. Using a small hydroxamate column, we have demonstrated an overall recovery of >50% of 45Ti in ~1 mL of 1M oxalic acid. Conditions for reacting with desferal were also explored, with effective specific activities up to 38 GBq/μmol obtained.

    Original languageEnglish
    JournalAIP Conference Proceedings - American Institute of Physics
    Volume1509
    Issue number1
    Pages (from-to)211-214
    ISSN0094-243x
    DOIs
    Publication statusPublished - 2012
    Event14th International Workshop on Targetry and Target Chemistry - Playa del Carmen, Mexico
    Duration: 26 Aug 201229 Aug 2012
    Conference number: 14

    Conference

    Conference14th International Workshop on Targetry and Target Chemistry
    Number14
    CountryMexico
    CityPlaya del Carmen
    Period26/08/201229/08/2012

    Keywords

    • Cyclotron
    • 45Ti production
    • Scandium
    • Hydroxamate resin
    • Desferal
    • Chelation
    • Positron emitter

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