Streptopyrrole: An antimicrobial metabolite from Streptomyces armeniacus

J. Breinholt, Hanne Gürtler, Anders Kjær, Salka E. Nielsen, C.E. Olsen

    Research output: Contribution to journalJournal articleResearchpeer-review


    A colourless, crystalline metabolite, C14H12ClNO4, named streptopyrrole, has been isolated from submerged fermentation cultures of Streptomyces armeniacus by extraction, followed by chromatographic purification. Its tricyclic molecular framework, seemingly without natural product precedents. as well as its substitution pattern were derived from extensive NMR analysis including H-1-detected INADEQUATE experiments. Streptopyrrole exhibits weak growth inhibitory effect towards a broad range of microorganisms.
    Original languageEnglish
    JournalActa Chemica Scandinavica
    Issue number8
    Pages (from-to)1040-1044
    Publication statusPublished - 1998


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