Strategies for differentiating infection in vaccinated animals (DIVA) for foot-and-mouth disease, classical swine fever and avian influenza

Åse Uttenthal, Satya Parida, Thomas Bruun Rasmussen, David Paton, Bernt Haas, William Dundon

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The prophylactic use of vaccines against exotic viral infections in production animals is undertaken exclusively in regions where the disease concerned is endemic. In such areas, the infection pressure is very high and so, to assure optimal protection, the most efficient vaccines are used. However, in areas considered to be free from these diseases and in which there is the possibility of only limited outbreaks, the use of Differentiation of Infected from Vaccinated Animals (DIVA) or marker vaccines allows for vaccination while still retaining the possibility of serological surveillance for the presence of infection. This literature review describes the current knowledge on the use of DIVA diagnostic strategies for three important transboundary animal diseases: foot-and-mouth disease in cloven-hoofed animals, classical swine fever in pigs and avian influenza in poultry.
    Original languageEnglish
    JournalExpert Review of Vaccines
    Volume9
    Issue number1
    Pages (from-to)73-87
    ISSN1476-0584
    DOIs
    Publication statusPublished - 2010

    Keywords

    • Classical swine fever
    • DIVA diagnostics
    • avian influenza
    • Foot and mouth disease

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