Abstract
This paper describes the development of a new variant of stereoselective strain-release driven reactions (formal homo [3 + 2] dipolar cycloadditions) which utilize housane (1) to construct functionalized amino alcohols and pyridine-substituted cyclopentanes in two to three steps from simple and easily available building blocks (nitrones and pyridine N-oxides respectively).
Original language | English |
---|---|
Journal | Organic Letters |
Volume | 21 |
Issue number | 12 |
Pages (from-to) | 4763-4766 |
Number of pages | 4 |
ISSN | 1523-7060 |
DOIs | |
Publication status | Published - 2019 |