Squalene in skin wipes: dependence on ozone, indoor climate and skin coverage

Sarka Langer*, Ann Sjöblom, Georgios Giovanoulis, Gabriel Bekö, Pawel Wargocki, Glenn Morrison, Charles J. Weschler, Jonathan Williams

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

    Abstract

    This study investigated net squalene depletion in skin surface lipids of volunteers during indoor ozone exposure in a climate chamber under different levels of temperature, relative humidity (RH) and clothing coverage. Squalene and cholesterol were quantified in skin wipes collected prior to and after the exposure. Squalene, normalized by cholesterol, decreased after exposure to ozone to ~ 90-65% of its original value for all combinations of experimental conditions. The results show measurable and meaningful depletion of squalene in skin surface lipids upon indoor ozone exposure.
    Original languageEnglish
    Title of host publicationProceedings of Indoor Air 2022
    Number of pages2
    PublisherInternational Society of Indoor Air Quality and Climate
    Publication date2022
    Article number1162
    Publication statusPublished - 2022
    Event17th International Conference of the International Society of Indoor Air Quality & Climate - University of Eastern Finland, Kuopio, Finland
    Duration: 12 Jun 202216 Jun 2022
    Conference number: 17
    https://indoorair2022.org/

    Conference

    Conference17th International Conference of the International Society of Indoor Air Quality & Climate
    Number17
    LocationUniversity of Eastern Finland
    Country/TerritoryFinland
    CityKuopio
    Period12/06/202216/06/2022
    Internet address

    Keywords

    • Skin surface lipids
    • Skin wipes
    • Squalene
    • Ozone
    • Exposure

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