Spray drying of low-phenylalanine skim milk: optimisation of process conditions for improving solubility and particle size: Optimisation of solubility and particle size

Atefeh Amiri-Rigi, Zahra Emam-Djomeh, Mohammad Amin Mohammadifar, Mehrdad Mohammadi

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The optimisation of the spray drying process for low-phenylalanine skim milk as a dietary supplement for phenylketonurics was studied. The effects of basic parameters including the inlet air temperature (100, 150 and 200 degrees C), feed flow rate (5, 10 and 15 mL min-1) and air flow rate (400, 600 and 800 L h-1) on the solubility and particle size of the low-phenylalanine skim milk powder were determined using response surface methodology. The optimum conditions have been obtained with inlet air temperature of 133 degrees C, feed flow rate of 5 mL min-1, and air flow rate of 800 L h-1. With the optimum parameters, the predicted values for the solubility and mean diameter were 95.33% and 5.34 mu m, respectively, and experimentally were 94.36 +/- 1.62% and 5.50 +/- 0.44 mu m, respectively. The experimental and predictive values were closely related showing predictive accuracy of the models.
Original languageEnglish
JournalInternational Journal of Food Science and Technology
Volume47
Issue number3
Pages (from-to)495-503
Number of pages9
ISSN0950-5423
DOIs
Publication statusPublished - 2012
Externally publishedYes

Keywords

  • Food Science
  • Industrial and Manufacturing Engineering
  • Low-phenylalanine milk powder
  • Particle size
  • Response surface methodology
  • Solubility
  • Spray drying
  • Air flow-rate
  • Basic parameters
  • Dietary supplements
  • Feed flow rate
  • Inlet air temperatures
  • Mean diameter
  • Milk powder
  • Optimisations
  • Optimum conditions
  • Optimum parameters
  • Predictive accuracy
  • Predictive values
  • Process condition
  • Response Surface Methodology
  • Skim milk powder
  • Skim milks
  • Spray drying process
  • With inlets
  • Air
  • Flow rate
  • Optimization
  • Surface properties
  • Thermal load
  • Amino acids
  • FOOD
  • PHYSICAL-PROPERTIES
  • DEHUMIDIFIED AIR
  • TOMATO PULP
  • POWDER
  • JUICE
  • VARIABLES
  • PRODUCT
  • particle size
  • response surface methodology
  • solubility
  • spray drying
  • air flow rate
  • feed flow rate
  • inlet air temperature
  • particle size improvement
  • process condition optimization
  • solubility factor
  • spray drying process
  • phenylketonuria Phenylketonurias (MeSH) nervous system disease, genetic disease, behavioral and mental disorders, metabolic disease, congenital disease diet therapy
  • Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common
  • low-phenylalanine skim milk powder dietary supplement
  • 03508, Genetics - Human
  • 04500, Mathematical biology and statistical methods
  • 07004, Behavioral biology - Human behavior
  • 10515, Biophysics - Biocybernetics
  • 12512, Pathology - Therapy
  • 13002, Metabolism - General metabolism and metabolic pathways
  • 13020, Metabolism - Metabolic disorders
  • 13202, Nutrition - General studies, nutritional status and methods
  • 20506, Nervous system - Pathology
  • 21002, Psychiatry - Psychopathology, psychodynamics and therapy
  • 25503, Development and Embryology - Pathology
  • Allied Medical Sciences
  • Computational Biology
  • Human Medicine, Medical Sciences
  • empirical model mathematical and computer techniques
  • polynomial model mathematical and computer techniques
  • response surface method mathematical and computer techniques
  • Medical Genetics
  • Metabolism
  • Models and Simulations
  • Neurology
  • Nutrition
  • Psychiatry
  • AMINO ACIDS
  • DIETETIC FOODS
  • DRIED FOODS
  • INSTANT FOODS
  • MILK
  • PARTICLES
  • PHENYLALANINE
  • PHYSICAL PROPERTIES
  • SIZE
  • SKIM MILK POWDERS
  • SOLUBILITY
  • SPRAY DRYING
  • Market milk
  • Milk and dairy products
  • SKIM milk

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