Speckle reduction in optical coherence tomography images of human skin by a spatial diversity method - art. no. 66270P

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review


    A range of compounding techniques have been suggested for dealing with the signal degrading speckle noise in optical coherence tomography (OCT). Recent implementations of angular compounding have shown great promise, but some of the implementations require substantial modifications of the OCT system. Here, we consider a method that in principle can be fitted to most OCT systems without major modifications. Specifically, we address a spatial diversity technique for suppressing speckle noise in OCT images of human skin. The method is a variant of changing the position of the sample relative to the measuring probe. Instead of physically moving the sample, which is often not feasible for in vivo imaging, the position of the focal plane of the probe beam is shifted. If the numerical aperture is sufficiently high this spatial diversity scheme incorporates a variant of angular compounding. We have tested the scheme with a mobile fiber-based time-domain real-time OCT system. Essential enhancement was obtained in image contrast when performing in vivo imaging of normal skin and lesions. Resulting images show improved delineation of structure in correspondence with the observed improvements in contrast-to-noise ratios.
    Original languageEnglish
    Title of host publicationOptical coherence tomography and coherence techniques 3
    EditorsP.E. Andersen, Z. Chen
    Place of PublicationBellingham
    PublisherInternational Society for Optical Engineering
    Publication date2007
    ISBN (Print)08-19-46771-3
    Publication statusPublished - 2007
    EventEuropean Conferences on Biomedical Optics 2007 - International Conference Centre Munich, Munich, Germany
    Duration: 17 Jun 200721 Jun 2007


    ConferenceEuropean Conferences on Biomedical Optics 2007
    LocationInternational Conference Centre Munich
    SeriesSPIE Proceedings Series, 6627


    Dive into the research topics of 'Speckle reduction in optical coherence tomography images of human skin by a spatial diversity method - art. no. 66270P'. Together they form a unique fingerprint.

    Cite this