TY - JOUR
T1 - Speciation with gene flow in equids despite extensive chromosomal plasticity
AU - Jáónsson, Hákon
AU - Schubert, Mikkel
AU - Seguin-Orlando, Andaine
AU - Ginolhac, Auráóélien
AU - Petersen, Lillian
AU - Fumagalli, Matteo
AU - Albrechtsen, Anders
AU - Petersen, Bent
AU - Korneliussen, Thorfinn S.
AU - Vilstrup, Julia T.
AU - Lear, Teri
AU - Myka, Jennifer Leigh
AU - Lundquist, Judith
AU - Miller, Donald C.
AU - Alfarhan, Ahmed H.
AU - Alquraishi, Saleh A.
AU - Al-Rasheid, Khaled A. S.
AU - Stagegaard, Julia
AU - Strauss, Günter
AU - Bertelsen, Mads Frost
AU - Sicheritz-Pontén, Thomas
AU - Antczak, Douglas F.
AU - Bailey, Ernest
AU - Nielsen, Rasmus
AU - Willerslev, Eske
AU - Orlando, Ludovic
PY - 2014
Y1 - 2014
N2 - Significance Thirty years after the first DNA fragment from the extinct quagga zebra was sequenced, we set another milestone in equine genomics by sequencing its entire genome, along with the genomes of the surviving equine species. This extensive dataset allows us to decipher the genetic makeup underlying lineage-specific adaptations and reveal the complex history of equine speciation. We find that Equus first diverged in the New World, spread across the Old World 2.1–3.4 Mya, and finally experienced major demographic expansions and collapses coinciding with past climate changes. Strikingly, we find multiple instances of hybridization throughout the equine tree, despite extremely divergent chromosomal structures. This contrasts with theories promoting chromosomal incompatibilities as drivers for the origin of equine species.
AB - Significance Thirty years after the first DNA fragment from the extinct quagga zebra was sequenced, we set another milestone in equine genomics by sequencing its entire genome, along with the genomes of the surviving equine species. This extensive dataset allows us to decipher the genetic makeup underlying lineage-specific adaptations and reveal the complex history of equine speciation. We find that Equus first diverged in the New World, spread across the Old World 2.1–3.4 Mya, and finally experienced major demographic expansions and collapses coinciding with past climate changes. Strikingly, we find multiple instances of hybridization throughout the equine tree, despite extremely divergent chromosomal structures. This contrasts with theories promoting chromosomal incompatibilities as drivers for the origin of equine species.
KW - Equids
KW - Evolutionary genomics
KW - Speciation
KW - Admixture
KW - Chromosomal rearrangements
U2 - 10.1073/pnas.1412627111
DO - 10.1073/pnas.1412627111
M3 - Journal article
SN - 0027-8424
VL - 111
SP - 18655
EP - 18660
JO - Proceedings of the National Academy of Sciences
JF - Proceedings of the National Academy of Sciences
IS - 52
ER -