Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

Troels Bjerre; Mads Fogtmann Hansen; M. Aznar; P. Munck af Rosenschold; L. Specht; Rasmus Larsen

doi:10.1109/ISBI.2012.6235782

Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

Troels Bjerre, Mads Fogtmann Hansen, M. Aznar, P. Munck af Rosenschold, L. Specht, Rasmus Larsen

Copenhagen University Hospital Herlev and Gentofte

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

Original language	English
Title of host publication	2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)
Publisher	IEEE
Publication date	2012
Pages	1224-1227
ISBN (Print)	978-1-4577-1857-1
DOIs	https://doi.org/10.1109/ISBI.2012.6235782
Publication status	Published - 2012
Event	2012 IEEE International Symposium on Biomedical Imaging - Barcelona, Spain Duration: 2 May 2012 → 5 May 2012 Conference number: 9 https://ieeexplore.ieee.org/xpl/conhome/6227656/proceeding

Conference

Conference	2012 IEEE International Symposium on Biomedical Imaging
Number	9
Country/Territory	Spain
City	Barcelona
Period	02/05/2012 → 05/05/2012
Internet address	https://ieeexplore.ieee.org/xpl/conhome/6227656/proceeding

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10.1109/ISBI.2012.6235782

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title = "Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy",

abstract = "For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.",

author = "Troels Bjerre and Hansen, {Mads Fogtmann} and M. Aznar and {af Rosenschold}, {P. Munck} and L. Specht and Rasmus Larsen",

year = "2012",

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booktitle = "2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)",

publisher = "IEEE",

address = "United States",

note = "2012 IEEE International Symposium on Biomedical Imaging, ISBI 2012 ; Conference date: 02-05-2012 Through 05-05-2012",

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Bjerre, T, Hansen, MF, Aznar, M, af Rosenschold, PM, Specht, L & Larsen, R 2012, Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy. in 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, pp. 1224-1227 , 2012 IEEE International Symposium on Biomedical Imaging, Barcelona, Spain, 02/05/2012. https://doi.org/10.1109/ISBI.2012.6235782

Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy. / Bjerre, Troels; Hansen, Mads Fogtmann; Aznar, M. et al.
2012 9th IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, 2012. p. 1224-1227 .

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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T1 - Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

AU - Bjerre, Troels

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AU - Specht, L.

AU - Larsen, Rasmus

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N2 - For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

AB - For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

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PB - IEEE

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Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

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