Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

Troels Bjerre, Mads Fogtmann Hansen, M. Aznar, P. Munck af Rosenschold, L. Specht, Rasmus Larsen

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.
    Original languageEnglish
    Title of host publication2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)
    PublisherIEEE
    Publication date2012
    Pages1224-1227
    ISBN (Print)978-1-4577-1857-1
    DOIs
    Publication statusPublished - 2012
    Event9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Barcelona, Spain
    Duration: 2 May 20125 May 2012
    http://www.biomedicalimaging.org/2012/
    https://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=17944

    Conference

    Conference9th IEEE International Symposium on Biomedical Imaging
    CountrySpain
    CityBarcelona
    Period02/05/201205/05/2012
    Internet address

    Cite this

    Bjerre, T., Hansen, M. F., Aznar, M., af Rosenschold, P. M., Specht, L., & Larsen, R. (2012). Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy. In 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI) (pp. 1224-1227 ). IEEE. https://doi.org/10.1109/ISBI.2012.6235782