The solubilityand density of NaHCO3 in the systems: monoethylene glycol (MEG)–water, diethylene glycol (DEG)–water, triethylene glycol (TEG)–water, and tetraethylene glycol (TeEG)–water have been measured over theentire concentration range from pure water to pure glycol. Experimentalmeasurements have been conducted at the temperatures 5, 20, 40, and60 °C and at atmospheric pressure. The solubility of NaHCO3 in all glycol mixtures increases with increasing temperatures.Solubility is largest in aqueous MEG and decreases with the highermolecular weights of glycol used. Local minima were observed in allsystems in the concentration range 80–90 wt % glycol, salt-free.On a mole fraction scale, minima were found at x(glycol,salt-free) = 0.5. There is a clear tendency that two solvate mechanismsexist with a 1:1 solvation relation. One type of solvation is formedin NaHCO3–water, and a second type is formed inNaHCO3–glycol. The density results showed a linearincrease up to a glycol concentration ≈80 wt %. Above 80 wt%, the density seemed to form a minima similar to the solubility phasediagrams.