Soft sensors in bioprocessing: A status report and recommendations

Reiner Luttmann, Daniel G. Bracewell, Gesine Cornelissen, Krist Gernaey, Jarka Glassey, Volker C. Hass, Christian Kaiser, Christian Preusse, Gerald Striedner, Carl-Fredrik Mandenius

Research output: Contribution to journalJournal articleResearchpeer-review


The following report with recommendations is the result of an expert panel meeting on soft sensor applications in bioprocess engineering that was organized by the Measurement, Monitoring, Modelling and Control (M3C) Working Group of the European Federation of Biotechnology - Section of Biochemical Engineering Science (ESBES). The aim of the panel was to provide an update on the present status of the subject and to identify critical needs and issues for the furthering of the successful development of soft sensor methods in bioprocess engineering research and for industrial applications, in particular with focus on biopharmaceutical applications. It concludes with a set of recommendations, which highlight current prospects for the extended use of soft sensors and those areas requiring development.
Original languageEnglish
JournalBiotechnology Journal
Issue number8, Sp. Iss. SI
Pages (from-to)1040-1048
Publication statusPublished - 2012

Bibliographical note

Special issue. Focus: Systems biology and personalized medicine


  • Soft sensors
  • Software sensors
  • Bioprocess engineering
  • Biochemical engineering
  • Control engineering

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