Sodium Dodecyl Sulfate (SDS)-Loaded Nanoporous Polymer as Anti-Biofilm Surface Coating Material

Li Li, Søren Molin, Liang Yang, Sokol Ndoni

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Biofilms cause extensive damage to industrial settings. Thus, it is important to improve the existing techniques and develop new strategies to prevent bacterial biofilm formation. In the present study, we have prepared nanoporous polymer films from a self-assembled 1,2-polybutadiene-b-polydimethylsiloxane (1,2-PB-b-PDMS) block copolymer via chemical cross-linking of the 1,2-PB block followed by quantitative removal of the PDMS block. Sodium dodecyl sulfate (SDS) was loaded into the nanoporous 1,2-PB from aqueous solution. The SDS-loaded nanoporous polymer films were shown to block bacterial attachment in short-term (3 h) and significantly reduce biofilm formation in long-term (1 week) by gram-negative bacterium Escherichia coli. Tuning the thickness or surface morphology of the nanoporous polymer films allowed to extent the anti-biofilm capability.
Original languageEnglish
JournalInternational Journal of Molecular Sciences (Online)
Issue number2
Pages (from-to)3050-3064
Publication statusPublished - 2013

Bibliographical note

International Journal of Molecular Sciences, an open access journal providing an advanced forum for chemistry, molecular physics and molecular biology, is published by MDPI online monthly.


  • Nanoporous polymer
  • SDS
  • Biofilm
  • Escherichia coli


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