Small hydrophobic protein drug conjugates and uses thereof

Mette Marie Rosenkilde; Katja Spiess; Lola Julie Torz Pedersen; Maja Lind Nybo Henningsen; Katrine Qvortrup

Small hydrophobic protein drug conjugates and uses thereof

Mette Marie Rosenkilde (Inventor), Katja Spiess (Inventor), Lola Julie Torz Pedersen (Inventor), Maja Lind Nybo Henningsen (Inventor), Katrine Qvortrup (Inventor)

IT University of Copenhagen

Research output: Patent

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Abstract

The present disclosure provides peptide conjugated drugs based on MuV SH Protein, their use as therapeutic agents and their use to provide delivery to and/or transfer across a membrane of the drug. The present disclosure provides use of the peptide conjugated drug for delivery of the drug to and/or across a membrane harbouring G protein-coupled receptor 125 (GPR125), such as the choroid plexus.

Original language	English
IPC	A61P 25/ 00 A I
Patent number	WO2022223837
Country/Territory	Denmark
Priority date	23/04/2021
Priority number	EP20210170192
Publication status	Published - 27 Oct 2022

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title = "Small hydrophobic protein drug conjugates and uses thereof",

abstract = "The present disclosure provides peptide conjugated drugs based on MuV SH Protein, their use as therapeutic agents and their use to provide delivery to and/or transfer across a membrane of the drug. The present disclosure provides use of the peptide conjugated drug for delivery of the drug to and/or across a membrane harbouring G protein-coupled receptor 125 (GPR125), such as the choroid plexus.",

author = "Rosenkilde, {Mette Marie} and Katja Spiess and Pedersen, {Lola Julie Torz} and Henningsen, {Maja Lind Nybo} and Katrine Qvortrup",

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T1 - Small hydrophobic protein drug conjugates and uses thereof

AU - Rosenkilde, Mette Marie

AU - Spiess, Katja

AU - Pedersen, Lola Julie Torz

AU - Henningsen, Maja Lind Nybo

AU - Qvortrup, Katrine

PY - 2022/10/27

Y1 - 2022/10/27

N2 - The present disclosure provides peptide conjugated drugs based on MuV SH Protein, their use as therapeutic agents and their use to provide delivery to and/or transfer across a membrane of the drug. The present disclosure provides use of the peptide conjugated drug for delivery of the drug to and/or across a membrane harbouring G protein-coupled receptor 125 (GPR125), such as the choroid plexus.

AB - The present disclosure provides peptide conjugated drugs based on MuV SH Protein, their use as therapeutic agents and their use to provide delivery to and/or transfer across a membrane of the drug. The present disclosure provides use of the peptide conjugated drug for delivery of the drug to and/or across a membrane harbouring G protein-coupled receptor 125 (GPR125), such as the choroid plexus.

M3 - Patent

M1 - WO2022223837

ER -

Small hydrophobic protein drug conjugates and uses thereof

Abstract

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