Sleep Spindles as Biomarker for Early Detection of Neurodegenerative Disorders

Julie Anja Engelhard Christensen (Inventor), Lykke Kempfner (Inventor), Poul Jørgen Jennum (Inventor), Helge Bjarup Dissing Sørensen (Inventor), Lars Arvastson (Inventor), Søren Rahn Christensen (Inventor)

Research output: Patent

134 Downloads (Pure)


The present invention relates to the use of sleep spindles as a novel biomarker for early diagnosis of synucleinopathies, in particular Parkinson's disease (PD). The method is based on automatic detection of sleep spindles. The method may be combined with measurements of one or more further biomarkers derived from polysomnographic recordings.

Original languageEnglish
IPCA61B5/00, A61B5/0476, A61B5/0496, A61B5/11
Patent numberUS2015080671
Filing date19/03/2015
CountryUnited States
Priority date29/05/2013
Priority numberEP20130169679
Publication statusPublished - 19 Mar 2015

Bibliographical note

Also registered as: US201414290402, EP20130169679


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