Skin symptoms among workers in the fish processing industry are caused by high molecular weight compounds

Inger Dalsgaard, Lars Halkier-Sørensen, Lene Heickendorff, Kristian Thestrup-Pedersen

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Abstract

Scratch tests were performed with fish juice containing high and low molecular weight compounds obtained by ultrafiltration and with degradation compounds known to accumulate in fish stored on ice. 75 volunteers were tested. The peptide pattern in raw fish juice and its high and low molecular weight fractions were analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and the concentration of protein in the various fractions was determined. Fish products were analysed for bacteria and algae and the concentration of degradation compounds was measured. Mainly high molecular weight compounds (polypeptides) of fish juice were found to be responsible for the skin symptoms.
Original languageEnglish
JournalContact Dermatitis
Volume24
Issue number2
Pages (from-to)94-100
ISSN0105-1873
Publication statusPublished - 1991
Externally publishedYes

Cite this

Dalsgaard, I., Halkier-Sørensen, L., Heickendorff, L., & Thestrup-Pedersen, K. (1991). Skin symptoms among workers in the fish processing industry are caused by high molecular weight compounds. Contact Dermatitis, 24(2), 94-100.