Singular value decomposition as a tool for background corrections in time-resolved XFEL scattering data

Research output: Contribution to journalJournal article – Annual report year: 2014Researchpeer-review

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The development of new X-ray light sources, XFELs, with unprecedented time and brilliance characteristics has led to the availability of very large datasets with high time resolution and superior signal strength. The chaotic nature of the emission processes in such sources as well as entirely novel detector demands has also led to significant challenges in terms of data analysis. This paper describes a heuristic approach to datasets where spurious background contributions of a magnitude similar to (or larger) than the signal of interest prevents conventional analysis approaches. The method relies on singular-value decomposition of no-signal subsets of acquired datasets in combination with model inputs and appears generally applicable to time-resolved X-ray diffuse scattering experiments.
Original languageEnglish
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume369
Issue number1647
ISSN0962-8436
DOIs
Publication statusPublished - 2014
CitationsWeb of Science® Times Cited: No match on DOI

    Research areas

  • Macromolecular assemblies, Symmetry, X-ray lasers, Manifold embedding, Dimensionality reduction

ID: 101395414