TY - JOUR
T1 - SEROTYPES AND ANTIMICROBIAL RESISTANCE OF SALMONELLA ENTERICA SSP IN CENTRAL THAILAND, 2001-2006
AU - Pantip, Sirichote
AU - Aroon, B.
AU - Kanokwan, Tienmanee
AU - Akawat, Unahaleka
AU - Amornrat, Uhright
AU - Patchree, Chittaphithakchai
AU - Wachirapa, Keawrod
AU - Hendriksen, Rene S.
PY - 2010
Y1 - 2010
N2 - This study was carried out to elucidate the epidemiological trends and
antimicrobial susceptibilities against Salmonella serovars among Thai patients and
asymptomatic carriers during 2001-2006 in central Thailand. A total of 1,401 human
and 260 non-human isolates from various sources were included. The isolates
were characterized using serotyping and antimicrobial susceptibility testing.
The most common serovars in patients submitting stool samples were
S. Weltevreden, S. Stanley, S. Anatum, and S. Rissen. Significantly higher odds
ratios were observed in blood samples versus stool sample for S. Choleraesuis,
S. Enteritidis, S. Typhimurium, and S. Typhi. Children under five years old suffered
the most frequently from gastroenteritis. The patients most commonly infected
with an invasive serovar were children and people from 26 to 55 years of
age. Antimicrobial susceptibility data revealed that S. Schwarzengrund, S.
Choleraesuis, S. Anatum, S. Stanley, S. Rissen, and S. Typhimurium were the most
resistant serovars observed. The invasive serovar, S. Choleraesuis was resistant to
cefotaxime and norfloxacin. Antimicrobial resistance to cefotaxime, was observed
in S. Agona, S. Rissen, S. Typhimurium, S. Anatum, and S. Weltevreden. An alarmingly
high frequency of resistance to third generation cephalosporins was observed.
We recommend Thai authorities take action in order to prevent spread of resistant
S. Choleraesuis and other serovars among animals and humans by enforcing a
more strict policy on the use of antimicrobials in food animals.
AB - This study was carried out to elucidate the epidemiological trends and
antimicrobial susceptibilities against Salmonella serovars among Thai patients and
asymptomatic carriers during 2001-2006 in central Thailand. A total of 1,401 human
and 260 non-human isolates from various sources were included. The isolates
were characterized using serotyping and antimicrobial susceptibility testing.
The most common serovars in patients submitting stool samples were
S. Weltevreden, S. Stanley, S. Anatum, and S. Rissen. Significantly higher odds
ratios were observed in blood samples versus stool sample for S. Choleraesuis,
S. Enteritidis, S. Typhimurium, and S. Typhi. Children under five years old suffered
the most frequently from gastroenteritis. The patients most commonly infected
with an invasive serovar were children and people from 26 to 55 years of
age. Antimicrobial susceptibility data revealed that S. Schwarzengrund, S.
Choleraesuis, S. Anatum, S. Stanley, S. Rissen, and S. Typhimurium were the most
resistant serovars observed. The invasive serovar, S. Choleraesuis was resistant to
cefotaxime and norfloxacin. Antimicrobial resistance to cefotaxime, was observed
in S. Agona, S. Rissen, S. Typhimurium, S. Anatum, and S. Weltevreden. An alarmingly
high frequency of resistance to third generation cephalosporins was observed.
We recommend Thai authorities take action in order to prevent spread of resistant
S. Choleraesuis and other serovars among animals and humans by enforcing a
more strict policy on the use of antimicrobials in food animals.
M3 - Journal article
VL - 41
SP - 1405
EP - 1415
JO - Southeast Asian Journal of Tropical Medicine and Public Health
JF - Southeast Asian Journal of Tropical Medicine and Public Health
SN - 0125-1562
IS - 6
ER -