TY - JOUR
T1 - Serological response to vaccination against avian influenza in zoo-birds using an inactivated H5N9 vaccine
AU - Bertelsen, Mads F.
AU - Klausen, Joan
AU - Holm, Elisabeth
AU - Grondahl, Carsten
AU - Jørgensen, Poul Henrik
PY - 2007
Y1 - 2007
N2 - Five hundred and forty birds in three zoos were vaccinated twice against avian influenza with a 6-week interval using an inactivated H5N9 vaccine. Serological response was evaluated by hemagglutination inhibition test 4-6 weeks following the second vaccine administration. 84% of the birds seroconverted, and 76% developed a titre >= 32. The geometric mean titre after vaccination was 137. A significant species variation in response was noted; penguins, pelicans, ducks, geese, herons, Guinea fowl, cranes, cockatiels, lovebirds, and barbets showed very poor response to vaccination, while very high titres and seroconversion rates were seen in flamingos, ibis, rheas, Congo peafowl, black-winged stilts, amazon parrots, and kookaburras.
AB - Five hundred and forty birds in three zoos were vaccinated twice against avian influenza with a 6-week interval using an inactivated H5N9 vaccine. Serological response was evaluated by hemagglutination inhibition test 4-6 weeks following the second vaccine administration. 84% of the birds seroconverted, and 76% developed a titre >= 32. The geometric mean titre after vaccination was 137. A significant species variation in response was noted; penguins, pelicans, ducks, geese, herons, Guinea fowl, cranes, cockatiels, lovebirds, and barbets showed very poor response to vaccination, while very high titres and seroconversion rates were seen in flamingos, ibis, rheas, Congo peafowl, black-winged stilts, amazon parrots, and kookaburras.
KW - exotic birds
KW - H5N9
KW - vaccination
KW - avian influenza
U2 - 10.1016/j.vaccine.2007.03.043
DO - 10.1016/j.vaccine.2007.03.043
M3 - Journal article
C2 - 17467857
SN - 0264-410X
VL - 25
SP - 4345
EP - 4349
JO - Vaccine
JF - Vaccine
IS - 22
ER -
