TY - JOUR
T1 - Separation of xylose and glucose using an integrated membrane system for enzymatic cofactor regeneration and downstream purification
AU - Morthensen, Sofie Thage
AU - Sigurdardóttir, Sigyn Björk
AU - Meyer, Anne S.
AU - Jørgensen, Henning
AU - Pinelo, Manuel
PY - 2017
Y1 - 2017
N2 - Mixtures of xylose, glucose and pyruvate were fed to a membrane bioreactor equipped with a charged NF membrane (NTR 7450). Value-added products were obtained in the reactor via enzymatic cofactor-dependent catalysis of glucose to gluconic acid and pyruvate to lactic acid, respectively. The initial cofactor (NADH) concentration could be decreased to 10% of the stoichiometric value (relative to glucose) without compromising process time and substrate conversion via i) efficient cofactor regeneration and ii) high retention of cofactor (R=0.98) in the membrane bioreactor. Furthermore, accumulation of xylose (R
AB - Mixtures of xylose, glucose and pyruvate were fed to a membrane bioreactor equipped with a charged NF membrane (NTR 7450). Value-added products were obtained in the reactor via enzymatic cofactor-dependent catalysis of glucose to gluconic acid and pyruvate to lactic acid, respectively. The initial cofactor (NADH) concentration could be decreased to 10% of the stoichiometric value (relative to glucose) without compromising process time and substrate conversion via i) efficient cofactor regeneration and ii) high retention of cofactor (R=0.98) in the membrane bioreactor. Furthermore, accumulation of xylose (R
KW - Biorefinery products
KW - Cofactor regeneration
KW - Membrane bioreactor
KW - Nanofiltration
KW - Sugars
U2 - 10.1016/j.memsci.2016.10.017
DO - 10.1016/j.memsci.2016.10.017
M3 - Journal article
SN - 0376-7388
VL - 523
SP - 327
EP - 335
JO - Journal of Membrane Science
JF - Journal of Membrane Science
ER -