Sensitivity of Process Design due to Uncertainties in Property Estimates

Amol Hukkerikar, Mark Nicholas Jones, Bent Sarup, Jens Abildskov, Gürkan Sin, Rafiqul Gani

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Abstract

The objective of this paper is to present a systematic methodology for performing analysis of sensitivity of process design due to uncertainties in property estimates. The methodology provides the following results: a) list of properties with critical importance on design; b) acceptable levels of accuracy for different thermo-physical property prediction models; and c) design variables versus properties relationships. The application of the methodology is illustrated through a case study of an extractive distillation process and sensitivity analysis of designs of various unit operations found in chemical processes. Among others vapour pressure accuracy for azeotropic mixtures is critical and needs to be measured or estimated with a ±0.25% accuracy to satisfy acceptable safety levels in design.
Original languageEnglish
Title of host publicationProceedings of the 11th International Symposium on Process Systems Engineering
EditorsI.A. Karimi, Rajagopalan Srinivasan
PublisherElsevier
Publication date2012
Pages200-204
Publication statusPublished - 2012
Event11th International Symposium on Process Systems Engineering - , Singapore
Duration: 15 Jul 201219 Jul 2012

Conference

Conference11th International Symposium on Process Systems Engineering
CountrySingapore
Period15/07/201219/07/2012
SeriesComputer Aided Chemical Engineering
Volume31
ISSN1570-7946

Keywords

  • Process design
  • Sensitivity analysis
  • Uncertainty
  • Property prediction

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