TY - JOUR
T1 - Self-Cross-Linkable Chitosan-Alginate Complexes Inspired by Mussel Glue Chemistry
AU - Kang, Junjie
AU - Zajforoushan Moghaddam, Saeed
AU - Thormann, Esben
N1 - Publisher Copyright:
© 2023 American Chemical Society.
PY - 2023
Y1 - 2023
N2 - In this study, mussel-inspired chemistry, based on catechol-amine reactions, was adopted to develop self-cross-linkable chitosan-alginate (Chi-Alg) complexes. To do so, the biopolymers were each substituted with ∼20% catechol groups (ChiC and AlgC), and then four complex combinations (Chi-Alg, ChiC-Alg, Chi-AlgC, ChiC-AlgC) were prepared at the surface and in bulk solution. Based on QCM-D and lap shear adhesion tests, the complex with catechol only on Chi (ChiC-Alg) did not show a significant variation from the control complex (Chi-Alg). Conversely, the complexes with catechol on alginate (Chi-AlgC and ChiC-AlgC) rendered a self-cross-linking property and enhanced cohesive properties.
AB - In this study, mussel-inspired chemistry, based on catechol-amine reactions, was adopted to develop self-cross-linkable chitosan-alginate (Chi-Alg) complexes. To do so, the biopolymers were each substituted with ∼20% catechol groups (ChiC and AlgC), and then four complex combinations (Chi-Alg, ChiC-Alg, Chi-AlgC, ChiC-AlgC) were prepared at the surface and in bulk solution. Based on QCM-D and lap shear adhesion tests, the complex with catechol only on Chi (ChiC-Alg) did not show a significant variation from the control complex (Chi-Alg). Conversely, the complexes with catechol on alginate (Chi-AlgC and ChiC-AlgC) rendered a self-cross-linking property and enhanced cohesive properties.
U2 - 10.1021/acs.langmuir.3c01750
DO - 10.1021/acs.langmuir.3c01750
M3 - Journal article
C2 - 37870990
AN - SCOPUS:85176495186
SN - 0743-7463
VL - 39
SP - 15499−15506
JO - Langmuir
JF - Langmuir
ER -