TY - JOUR
T1 - Selective halogen-lithium exchange reaction of bromine-substituted 25,26,27,28-tetrapropoxycalix[4]arene
AU - Larsen, M.
AU - Jørgensen, M.
PY - 1996
Y1 - 1996
N2 - Methods are described for the selective bromine-lithium exchange reaction of bromine-substituted calix[4]arenes with either n-BuLi or t-BuLi in THF. Quenching of the lithiated calix[4]arenes with MeOH, D2O, CH3SSCH3, B(OCHg3)3, DMF, or CO2 as electrophiles resulted in 5-monosubstituted, 5,17-disubstituted, or 5,11,17,23-tetrasubstituted calix[4]arenes with H, D, SCH3, B(OH)2, CHO, or COOH functionalities.
AB - Methods are described for the selective bromine-lithium exchange reaction of bromine-substituted calix[4]arenes with either n-BuLi or t-BuLi in THF. Quenching of the lithiated calix[4]arenes with MeOH, D2O, CH3SSCH3, B(OCHg3)3, DMF, or CO2 as electrophiles resulted in 5-monosubstituted, 5,17-disubstituted, or 5,11,17,23-tetrasubstituted calix[4]arenes with H, D, SCH3, B(OH)2, CHO, or COOH functionalities.
KW - Materialer med særlige fysiske og kemiske egenskaber; Nye funktionelle materialer
U2 - 10.1021/jo9609440
DO - 10.1021/jo9609440
M3 - Journal article
SN - 0022-3263
VL - 61
SP - 6651
EP - 6655
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 19
ER -