Scanning conductance microscopy investigations on fixed human chromosomes

Casper Hyttel Clausen, Jacob Moresco Lange, Linda Boye Jensen, Pranjul Jaykumar Shah, M. I. Dimaki, Winnie Edith Svendsen

    Research output: Contribution to journalJournal articleResearchpeer-review


    Scanning conductance microscopy investigations were carried out in air on human chromosomes fixed on pre-fabricated SiO2 surfaces with a backgate. The point of the investigation was to estimate the dielectric constant of fixed human chromosomes in order to use it for microfluidic device optimization. The phase shift caused by the electrostatic forces, together with geometrical measurements of the atomic force microscopy (AFM) cantilever and the chromosomes were used to estimate a value,for the dielectric constant of different human chromosomes.
    Original languageEnglish
    Issue number2
    Pages (from-to)225-228
    Publication statusPublished - 2008


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