Resistance of Salmonds Against Aeromonas Salmonicida: Host Genetics as a Main Player

Lars Holten-Andersen, Inger Dalsgaard, Kurt Buchmann

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    Abstract

    Furunculosis, caused by Aeromonas salmonicida, continues to be a health problem for the growing salmonid aquaculture. Despite effective vaccination programs regular outbreaks occur at Danish trout farms calling for repeated antibiotic treatment. We hypothesized that a difference in natural susceptibility to this disease might exist between Baltic salmon and the widely used rainbow trout. Hence, a cohabitation challenge model was applied to investigate the relative susceptibility to infection with Aeromonas salmonicida in rainbow trout and Baltic salmon. The course of infection was monitored daily over a 30-day period post challenge and the results were summarized in mortality curves. A. salmonicida was recovered from mortalities during the entire test period. At day 30 the survival was 6.2 % and 34.0 % for rainbow trout and Baltic salmon, respectively. Significant differences in susceptibility to A. salmonicida were demonstrated between the two salmonids and hazard ratio estimation between rainbow trout and Baltic salmon showed a 3.36 higher risk of dying from the infection in the former. The finding that Baltic salmon carries a high level of natural resistance to furunculosis might raise new possibilities for salmonid aquaculture in terms of minimizing disease outbreaks and the use of antibiotics.
    Original languageEnglish
    Title of host publicationBook of abstracts
    Number of pages18
    Place of PublicationFrederiksberg
    PublisherDAFINET
    Publication date2011
    Publication statusPublished - 2011
    EventDAFINET Workshop: The Ontogeny of the Immune System of Fish - Status and Future Challenges - Siemsens Gaard, Svaneke, Denmark
    Duration: 3 May 20115 May 2011

    Workshop

    WorkshopDAFINET Workshop
    LocationSiemsens Gaard
    CountryDenmark
    CitySvaneke
    Period03/05/201105/05/2011

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