Required ozone doses for removing pharmaceuticals from wastewater effluents

Maria Antoniou, Gerly Hey, Sergio Rodríguez Vega, Aikaterini Spiliotopoulou, Jerker Fick, Mats Tysklind, Jes la Cour Jansen, Henrik Rasmus Andersen

Research output: Contribution to journalJournal articleResearchpeer-review

690 Downloads (Pure)

Abstract

The aim of the this study was to investigate the ozone dosage required to remove active pharmaceutical ingredients (APIs) from biologically treated wastewater of varying quality, originated from different raw wastewater and wastewater treatment processes.Secondary effluents from six Swedish wastewater treatment plants (WWTP) were spiked with 42 APIs (nominal concentration 1μg/L) and treated with different O3 doses (0.5–12.0mg/L ozone) in bench-scale experiments.In order to compare the sensitivity of APIs in each matrix, the specific dose of ozone required to achieve reduction by one decade of each investigated API (DDO3) was determined for each effluent by fitting a first order equation to the remaining concentration of API at each applied ozone dose. Ozone dose requirements were found to vary significantly between effluents depending on their matrix characteristics.The specific ozone dose was then normalized to the dissolved organic carbon (DOC) of each effluent. The DDO3/DOC ratios were comparable for each API between the effluents.15 of the 42 investigated APIs could be classified as easily degradable (DDO3/DOC≤0.7), while 19 were moderately degradable (0.71.4). Furthermore, we predict that a reasonable estimate of the ozone dose required to remove any of the investigated APIs may be attained by multiplying the experimental average DDO3/DOC obtained with the actual DOC of any effluent.
Original languageEnglish
JournalScience of the Total Environment
Volume456-457
Pages (from-to)42-49
ISSN0048-9697
DOIs
Publication statusPublished - 2013

Keywords

  • Matrix effect
  • Ozonation
  • Ozone dose
  • Pharmaceuticals
  • Wastewater

Cite this

Antoniou, Maria ; Hey, Gerly ; Rodríguez Vega, Sergio ; Spiliotopoulou, Aikaterini ; Fick, Jerker ; Tysklind, Mats ; la Cour Jansen, Jes ; Andersen, Henrik Rasmus. / Required ozone doses for removing pharmaceuticals from wastewater effluents. In: Science of the Total Environment. 2013 ; Vol. 456-457. pp. 42-49.
@article{e7c6e2e01750469ba5d8c67a024d6f6b,
title = "Required ozone doses for removing pharmaceuticals from wastewater effluents",
abstract = "The aim of the this study was to investigate the ozone dosage required to remove active pharmaceutical ingredients (APIs) from biologically treated wastewater of varying quality, originated from different raw wastewater and wastewater treatment processes.Secondary effluents from six Swedish wastewater treatment plants (WWTP) were spiked with 42 APIs (nominal concentration 1μg/L) and treated with different O3 doses (0.5–12.0mg/L ozone) in bench-scale experiments.In order to compare the sensitivity of APIs in each matrix, the specific dose of ozone required to achieve reduction by one decade of each investigated API (DDO3) was determined for each effluent by fitting a first order equation to the remaining concentration of API at each applied ozone dose. Ozone dose requirements were found to vary significantly between effluents depending on their matrix characteristics.The specific ozone dose was then normalized to the dissolved organic carbon (DOC) of each effluent. The DDO3/DOC ratios were comparable for each API between the effluents.15 of the 42 investigated APIs could be classified as easily degradable (DDO3/DOC≤0.7), while 19 were moderately degradable (0.71.4). Furthermore, we predict that a reasonable estimate of the ozone dose required to remove any of the investigated APIs may be attained by multiplying the experimental average DDO3/DOC obtained with the actual DOC of any effluent.",
keywords = "Matrix effect, Ozonation, Ozone dose, Pharmaceuticals, Wastewater",
author = "Maria Antoniou and Gerly Hey and {Rodr{\'i}guez Vega}, Sergio and Aikaterini Spiliotopoulou and Jerker Fick and Mats Tysklind and {la Cour Jansen}, Jes and Andersen, {Henrik Rasmus}",
year = "2013",
doi = "10.1016/j.scitotenv.2013.03.072",
language = "English",
volume = "456-457",
pages = "42--49",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier",

}

Antoniou, M, Hey, G, Rodríguez Vega, S, Spiliotopoulou, A, Fick, J, Tysklind, M, la Cour Jansen, J & Andersen, HR 2013, 'Required ozone doses for removing pharmaceuticals from wastewater effluents', Science of the Total Environment, vol. 456-457, pp. 42-49. https://doi.org/10.1016/j.scitotenv.2013.03.072

Required ozone doses for removing pharmaceuticals from wastewater effluents. / Antoniou, Maria; Hey, Gerly; Rodríguez Vega, Sergio; Spiliotopoulou, Aikaterini; Fick, Jerker; Tysklind, Mats; la Cour Jansen, Jes; Andersen, Henrik Rasmus.

In: Science of the Total Environment, Vol. 456-457, 2013, p. 42-49.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Required ozone doses for removing pharmaceuticals from wastewater effluents

AU - Antoniou, Maria

AU - Hey, Gerly

AU - Rodríguez Vega, Sergio

AU - Spiliotopoulou, Aikaterini

AU - Fick, Jerker

AU - Tysklind, Mats

AU - la Cour Jansen, Jes

AU - Andersen, Henrik Rasmus

PY - 2013

Y1 - 2013

N2 - The aim of the this study was to investigate the ozone dosage required to remove active pharmaceutical ingredients (APIs) from biologically treated wastewater of varying quality, originated from different raw wastewater and wastewater treatment processes.Secondary effluents from six Swedish wastewater treatment plants (WWTP) were spiked with 42 APIs (nominal concentration 1μg/L) and treated with different O3 doses (0.5–12.0mg/L ozone) in bench-scale experiments.In order to compare the sensitivity of APIs in each matrix, the specific dose of ozone required to achieve reduction by one decade of each investigated API (DDO3) was determined for each effluent by fitting a first order equation to the remaining concentration of API at each applied ozone dose. Ozone dose requirements were found to vary significantly between effluents depending on their matrix characteristics.The specific ozone dose was then normalized to the dissolved organic carbon (DOC) of each effluent. The DDO3/DOC ratios were comparable for each API between the effluents.15 of the 42 investigated APIs could be classified as easily degradable (DDO3/DOC≤0.7), while 19 were moderately degradable (0.71.4). Furthermore, we predict that a reasonable estimate of the ozone dose required to remove any of the investigated APIs may be attained by multiplying the experimental average DDO3/DOC obtained with the actual DOC of any effluent.

AB - The aim of the this study was to investigate the ozone dosage required to remove active pharmaceutical ingredients (APIs) from biologically treated wastewater of varying quality, originated from different raw wastewater and wastewater treatment processes.Secondary effluents from six Swedish wastewater treatment plants (WWTP) were spiked with 42 APIs (nominal concentration 1μg/L) and treated with different O3 doses (0.5–12.0mg/L ozone) in bench-scale experiments.In order to compare the sensitivity of APIs in each matrix, the specific dose of ozone required to achieve reduction by one decade of each investigated API (DDO3) was determined for each effluent by fitting a first order equation to the remaining concentration of API at each applied ozone dose. Ozone dose requirements were found to vary significantly between effluents depending on their matrix characteristics.The specific ozone dose was then normalized to the dissolved organic carbon (DOC) of each effluent. The DDO3/DOC ratios were comparable for each API between the effluents.15 of the 42 investigated APIs could be classified as easily degradable (DDO3/DOC≤0.7), while 19 were moderately degradable (0.71.4). Furthermore, we predict that a reasonable estimate of the ozone dose required to remove any of the investigated APIs may be attained by multiplying the experimental average DDO3/DOC obtained with the actual DOC of any effluent.

KW - Matrix effect

KW - Ozonation

KW - Ozone dose

KW - Pharmaceuticals

KW - Wastewater

U2 - 10.1016/j.scitotenv.2013.03.072

DO - 10.1016/j.scitotenv.2013.03.072

M3 - Journal article

VL - 456-457

SP - 42

EP - 49

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -

Antoniou M, Hey G, Rodríguez Vega S, Spiliotopoulou A, Fick J, Tysklind M et al. Required ozone doses for removing pharmaceuticals from wastewater effluents. Science of the Total Environment. 2013;456-457:42-49. https://doi.org/10.1016/j.scitotenv.2013.03.072