Regulation of the mitogen-activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts.

Carlo G Ossum, Tune Wulff, Else K Hoffmann

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

It is well known from various mammalian cells that anoxia has a major impact on the mitogen-activated protein kinase ERK, but a possible similar effect in fish cells has not been investigated. Here we characterise a p44ERK-like protein in the rainbow trout cell line RTHDF and study the effect of (i) serum stimulation, (ii) sodium azide (chemical anoxia) and removal of azide (recovery) and (iii) anoxia (P(O)2
Original languageEnglish
JournalJournal of Experimental Biology
Volume209
Issue number9
Pages (from-to)1765-1776
ISSN0022-0949
Publication statusPublished - 2006
Externally publishedYes

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