Abstract
It is well known from various mammalian cells that anoxia has a major impact on the mitogen-activated protein kinase ERK, but a possible similar effect in fish cells has not been investigated. Here we characterise a p44ERK-like protein in the rainbow trout cell line RTHDF and study the effect of (i) serum stimulation, (ii) sodium azide (chemical anoxia) and removal of azide (recovery) and (iii) anoxia (P(O)2
Original language | English |
---|---|
Journal | Journal of Experimental Biology |
Volume | 209 |
Issue number | 9 |
Pages (from-to) | 1765-1776 |
ISSN | 0022-0949 |
Publication status | Published - 2006 |
Externally published | Yes |