Abstract
Amylases possess short, conserved regions near functional side chains. Sequence comparison extends this relationship to comprise a maltase and a cyclodextrin glucanotransferase. Similarity also exists with intestinal sucrase-isomaltase and fungal glucoamylase near identified essential carboxyl groups. Homology between COOH-terminal regions of glucoamylase and cyclodextrin glucanotranserase may indicate raw-starch binding areas. It is suggested that amylases, alpha-glucosidases, and transglucanosylases acting on 1,4- and 1,6-alpha-glucosidic linkages share key structural features in the active centres.
| Original language | English |
|---|---|
| Journal | F E B S Letters |
| Volume | 230 |
| Pages (from-to) | 72-76 |
| ISSN | 0014-5793 |
| Publication status | Published - 1988 |
| Externally published | Yes |