Regio- and stereoselective hydrosilylation of terminal alkynes on solid support using diisopropyl hydrosilanes yielding b-(E)-vinyl silanes with excellent selectivity is reported. The hydrosilylation is catalyzed by Pt(DVDS)/P(iBuNCH2CH2)3N (DVDS = 1,3-divinyl-1,1,3,3-tetramethyl-disiloxane), in which the bulky proazaphosphatrane ligand plays a key role for the selectivity. The immobilized products are characterized with gel phase 13C NMR and 1H high resolution magic angle spinning NMR.
Pedersen, P. J., Henriksen, J., Gotfredsen, C. H., & Clausen, M. H. (2008). Regio- and stereoselective hydrosilylation of immobilized terminal alkynes. Tetrahedron Letters, 49(43), 6220-6223. https://doi.org/10.1016/j.tetlet.2008.08.043