Recon 2.2: from reconstruction to model of human metabolism

Neil Swainston, Kieran Smallbone, Hooman Hefzi, Paul D. Dobson, Judy Brewer, Michael Hanscho, Daniel C. Zielinski, Kok Siong Ang, Natalie J. Gardiner, Jahir M. Gutierrez, Sarantos Kyriakopoulos, Meiyappan Lakshmanan, Shangzhong Li, Joanne K. Liu, Veronica S. Martínez, Camila A. Orellana, Lake Ee Quek, Alex Thomas, Juergen Zanghellini, Nicole BorthDong Yup Lee, Lars K. Nielsen, Douglas B. Kell, Nathan Lewis, Pedro Mendes

    Research output: Contribution to journalJournal article

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    Abstract

    The human genome-scale metabolic reconstruction details all known metabolic reactions occurring in humans, and thereby holds substantial promise for studying complex diseases and phenotypes. Capturing the whole human metabolic reconstruction is an on-going task and since the last community effort generated a consensus reconstruction, several updates have been developed.
    Original languageEnglish
    Article number109
    JournalMetabolomics
    Volume12
    Number of pages7
    ISSN1573-3882
    DOIs
    Publication statusPublished - 2016

    Bibliographical note

    The Author(s) 2016. This article is published with open access at Springerlink.com

    Keywords

    • Human
    • Metabolism
    • Modelling
    • Reconstruction
    • Model
    • Systems biology

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