Recombinant snake antivenoms get closer to the clinic

Andreas H. Laustsen

doi:10.1016/j.it.2024.03.001

Recombinant snake antivenoms get closer to the clinic

Andreas H. Laustsen^*

^*Corresponding author for this work

Department of Biotechnology and Biomedicine

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Snakebite envenomings kill ~100 000 victims each year and leave many more with permanent sequelae. Antivenoms have been available for more than 125 years but are in need of innovation. A new study by Khalek et al. highlights broadly neutralizing human monoclonal antibodies (mAbs) that might be used to develop recombinant antivenoms with superior therapeutic benefits.

Original language	English
Journal	Trends in Immunology
Volume	45
Issue number	4
Pages (from-to)	225-227
ISSN	1471-4906
DOIs	https://doi.org/10.1016/j.it.2024.03.001
Publication status	Published - 2024

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AB - Snakebite envenomings kill ~100 000 victims each year and leave many more with permanent sequelae. Antivenoms have been available for more than 125 years but are in need of innovation. A new study by Khalek et al. highlights broadly neutralizing human monoclonal antibodies (mAbs) that might be used to develop recombinant antivenoms with superior therapeutic benefits.

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Recombinant snake antivenoms get closer to the clinic

Abstract

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