Recent approaches towards the asymmetric synthesis of α,α-disubstituted α-amino acids

Henning Vogt, S. Brase

Research output: Contribution to journalReviewResearchpeer-review


The class of alpha,alpha-disubstituted alpha-amino acids has gained considerable attention in the past decades and continues doing so. The ongoing interest in biological and chemical properties of the substance class has inspired the development of many new methodologies for their asymmetric construction, which have not found their way into the general focus of organic chemistry yet. The aim of this review is to provide an overview of the developments in the field since 1998.
Original languageEnglish
JournalOrganic & Biomolecular Chemistry
Issue number3
Pages (from-to)406-430
Publication statusPublished - 2007

Cite this