Real-time optical monitoring of cell culture in centrifugal microfluidics

Edwin En Te Hwu*, Lina Gruzinskyte, Atsushi Ishimoto, Laura Serioli, Sriram Thoppe Rajendran, Akinobu Yamaguchi, Kinga Zor, Anja Boisen

*Corresponding author for this work

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Abstract

We present a cellular-resolution (2 Pm) optical microscope that is rotating with a disc-shaped centrifugal microfluidics cell culture platform, inside an incubator. The microscope is powered wirelessly and is composed of a homemade optics and a wireless spy camera. The human cervical cancer cell line was, seeded and cultured on the disc, where their attachment and growth was monitored with the microscope. The microscope can wirelessly transmit microscopic images through the incubator to an external PC, which enables real-time (30 frames per second), continuous (without time limit) and remote (live Internet streaming) monitoring of the cell-based assays.
Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Publication date2020
Pages1039-1040
ISBN (Electronic)978-173341901-7
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Online event
Duration: 4 Oct 20209 Oct 2020
Conference number: 24
https://microtasconferences.org/microtas2020/

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number24
LocationOnline event
Period04/10/202009/10/2020
Internet address

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