Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat

Kinga Zor; M. Vergani; Arto Heiskanen; E. Landini; M. Carminati; V. Coman; Indumathi Vedarethinam; Peder Skafte-Pedersen; Maciej Skolimowski; A. Martinez Serrano; M. Kokaia; T. Ramos Moreno; A. Ghio; Winnie Edith Svendsen; Maria Dimaki; Zs. Keresztes; M. Adamovski; U. Wollenberger; David Sabourin; G. Ferrari; R. Raiteri; M. Sampietro; Martin Dufva; Jenny Emnéus

Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat

Kinga Zor, M. Vergani, Arto Heiskanen, E. Landini, M. Carminati, V. Coman, Indumathi Vedarethinam, Peder Skafte-Pedersen, Maciej Skolimowski, A. Martinez Serrano, M. Kokaia, T. Ramos Moreno, A. Ghio, Winnie Edith Svendsen, Maria Dimaki, Zs. Keresztes, M. Adamovski, U. Wollenberger, David Sabourin, G. FerrariR. Raiteri, M. Sampietro, Martin Dufva, Jenny Emnéus

Technical University of Denmark

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Abstract

A versatile microfluidic, multichamber cell culture and analysis system with an integrated electrode array and potentiostat suitable for electrochemical detection and microscopic imaging is presented in this paper. The system, which allows on-line electrode cleaning and modification, was developed for real-time monitoring of cellular dynamics, exemplified in this work by monitoring of redox metabolism inside living yeast cells and dopamine release from PC12 cells.

Original language	English
Title of host publication	Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publication date	2011
Publication status	Published - 2011
Event	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Seattle, United States Duration: 2 Oct 2011 → 6 Oct 2011 Conference number: 15 https://microtasconferences.org/microtas2011/

Conference

Conference	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	15
Country/Territory	United States
City	Seattle
Period	02/10/2011 → 06/10/2011
Internet address	https://microtasconferences.org/microtas2011/

Keywords

Cellular Dynamics Monitoring
On-line Measurement
Dopamine Exocytosis
Microfluidic Cell Culture System

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Zor, K., Vergani, M., Heiskanen, A., Landini, E., Carminati, M., Coman, V., Vedarethinam, I., Skafte-Pedersen, P., Skolimowski, M., Martinez Serrano, A., Kokaia, M., Ramos Moreno, T., Ghio, A., Svendsen, W. E., Dimaki, M., Keresztes, Z., Adamovski, M., Wollenberger, U., Sabourin, D., ... Emnéus, J. (2011). Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat. In Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences

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title = "Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat",

abstract = "A versatile microfluidic, multichamber cell culture and analysis system with an integrated electrode array and potentiostat suitable for electrochemical detection and microscopic imaging is presented in this paper. The system, which allows on-line electrode cleaning and modification, was developed for real-time monitoring of cellular dynamics, exemplified in this work by monitoring of redox metabolism inside living yeast cells and dopamine release from PC12 cells.",

keywords = "Cellular Dynamics Monitoring, On-line Measurement, Dopamine Exocytosis, Microfluidic Cell Culture System",

author = "Kinga Zor and M. Vergani and Arto Heiskanen and E. Landini and M. Carminati and V. Coman and Indumathi Vedarethinam and Peder Skafte-Pedersen and Maciej Skolimowski and {Martinez Serrano}, A. and M. Kokaia and {Ramos Moreno}, T. and A. Ghio and Svendsen, {Winnie Edith} and Maria Dimaki and Zs. Keresztes and M. Adamovski and U. Wollenberger and David Sabourin and G. Ferrari and R. Raiteri and M. Sampietro and Martin Dufva and Jenny Emn{\'e}us",

year = "2011",

language = "English",

booktitle = "Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences",

note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",

url = "https://microtasconferences.org/microtas2011/",

}

Zor, K, Vergani, M, Heiskanen, A, Landini, E, Carminati, M, Coman, V, Vedarethinam, I, Skafte-Pedersen, P, Skolimowski, M, Martinez Serrano, A, Kokaia, M, Ramos Moreno, T, Ghio, A, Svendsen, WE , Dimaki, M, Keresztes, Z, Adamovski, M, Wollenberger, U, Sabourin, D, Ferrari, G, Raiteri, R, Sampietro, M, Dufva, M & Emnéus, J 2011, Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat. in Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, Washington, United States, 02/10/2011.

Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat. / Zor, Kinga; Vergani, M.; Heiskanen, Arto et al.
Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences. 2011.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat

AU - Zor, Kinga

AU - Vergani, M.

AU - Heiskanen, Arto

AU - Landini, E.

AU - Carminati, M.

AU - Coman, V.

AU - Vedarethinam, Indumathi

AU - Skafte-Pedersen, Peder

AU - Skolimowski, Maciej

AU - Martinez Serrano, A.

AU - Kokaia, M.

AU - Ramos Moreno, T.

AU - Ghio, A.

AU - Svendsen, Winnie Edith

AU - Dimaki, Maria

AU - Keresztes, Zs.

AU - Adamovski, M.

AU - Wollenberger, U.

AU - Sabourin, David

AU - Ferrari, G.

AU - Raiteri, R.

AU - Sampietro, M.

AU - Dufva, Martin

AU - Emnéus, Jenny

N1 - Conference code: 15

PY - 2011

Y1 - 2011

N2 - A versatile microfluidic, multichamber cell culture and analysis system with an integrated electrode array and potentiostat suitable for electrochemical detection and microscopic imaging is presented in this paper. The system, which allows on-line electrode cleaning and modification, was developed for real-time monitoring of cellular dynamics, exemplified in this work by monitoring of redox metabolism inside living yeast cells and dopamine release from PC12 cells.

AB - A versatile microfluidic, multichamber cell culture and analysis system with an integrated electrode array and potentiostat suitable for electrochemical detection and microscopic imaging is presented in this paper. The system, which allows on-line electrode cleaning and modification, was developed for real-time monitoring of cellular dynamics, exemplified in this work by monitoring of redox metabolism inside living yeast cells and dopamine release from PC12 cells.

KW - Cellular Dynamics Monitoring

KW - On-line Measurement

KW - Dopamine Exocytosis

KW - Microfluidic Cell Culture System

M3 - Article in proceedings

BT - Proceedings of International Conference on Miniaturized Systems for Chemistry and Life Sciences

T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 2 October 2011 through 6 October 2011

ER -

Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat

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Keywords

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