Reaction Engineering for the Industrial Implementation of Biocatalysis

John M. Woodley*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Biocatalytic processes (using one or more enzymes) for the production of chemicals is an important potential route to more sustainable manufacturing and today have found application in several industries, but most notably in the pharmaceutical sector. For high-priced pharmaceuticals, the development of new processes is primarily dependent upon enzyme development. However, the wider application of biocatalytic processes towards lower-priced chemicals will demand reaction engineering to be considered, alongside biocatalyst development. Bioreaction engineering should include an evaluation of the thermodynamics and reaction kinetics, as well as the stability of the biocatalyst. In this brief article, tools to assist in the collection and evaluation of reaction engineering data will be discussed, and illustrated using biological oxidation as an example.
Original languageEnglish
JournalTopics in catalysis
Volume62
Issue number17-20
Pages (from-to)1202-1207
Number of pages6
ISSN1022-5528
DOIs
Publication statusPublished - 2019

Keywords

  • Biocatalyst stability
  • Biocatalytic processes
  • Bioreaction engineering
  • Enzyme kinetics

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