Quantitative image analysis of microbial communities with BiofilmQ

Raimo Hartmann, Hannah Jeckel, Eric Jelli, Praveen K. Singh, Sanika Vaidya, Miriam Bayer, Daniel K. H. Rode, Lucia Vidakovic, Francisco Díaz-Pascual, Jiunn C. N. Fong, Anna Dragoš, Olga Lamprecht, Janne G. Thöming, Niklas Netter, Susanne Häussler, Carey D. Nadell, Victor Sourjik, Ákos T. Kovács, Fitnat H. Yildiz, Knut Drescher*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Biofilms are microbial communities that represent a highly abundant form of microbial life on Earth. Inside biofilms, phenotypic and genotypic variations occur in three-dimensional space and time; microscopy and quantitative image analysis are therefore crucial for elucidating their functions. Here, we present BiofilmQ—a comprehensive image cytometry software tool for the automated and high-throughput quantification, analysis and visualization of numerous biofilm-internal and whole-biofilm properties in three-dimensional space and time.
Original languageEnglish
JournalNature Microbiology
Volume6
Pages (from-to)151-156
Number of pages6
ISSN2058-5276
DOIs
Publication statusPublished - 2021

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