Qualitative Mapping of Structural Different Polypeptide Nanotubes

Casper Hyttel Clausen, Jason Jensen, Jaime Castillo, Maria Dimaki, Winnie Edith Svendsen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Biological self-assembled structures are receiving increasing focus within micro- and nanotechnology, for example, as sensing devices, due to the fact that they are cheap to produce and easy to functionalize. Therefore, methods for the characterization of these structures are much needed. In this paper, electrostatic force microscopy (EFM) was used to distinguish between hollow nanotubes formed by self-assembly by a simple aromatic dipeptide, L-phenylalanine, silver-filled peptide-based nanotubes, and silver wires placed on prefabricated SiO(2) surfaces with a backgate. The investigation shows that it is possible to distinguish between these three types of structures using this method. Further, an agreement between the detected signal and the structure of the hollow peptide was demonstrated; however only qualitative agreement with the mathematical expressing of the tubes is shown.
    Original languageEnglish
    JournalNano Letters
    Volume8
    Issue number11
    Pages (from-to)4066-4069
    ISSN1530-6984
    DOIs
    Publication statusPublished - 2008

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