PYROLYTIC PRODUCTS FROM TRYPTOPHAN AND GLUTAMIC-ACID ARE POSITIVE IN THE MAMMALIAN SPOT-TEST

Niels Juul Jensen

doi:10.1016/0304-3835(83)90055-1

PYROLYTIC PRODUCTS FROM TRYPTOPHAN AND GLUTAMIC-ACID ARE POSITIVE IN THE MAMMALIAN SPOT-TEST

Niels Juul Jensen

National Food Institute

Technical University of Denmark

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Pyrolysates of tryptophan (Trp-P-2) and glutamic acid (Glu-P-1) are known mutagens in in vitro short term mutagenicity tests, and have also shown carcinogenic effects in long term animal studies. The present study demonstrates that they also produce mutations in somatic cells. This result demonstrates the ability of the test to detect carcinogenic and mutagenic compounds.

Original language	English
Journal	Cancer Letters
Volume	20
Issue number	2
Pages (from-to)	241-244
ISSN	0304-3835
DOIs	https://doi.org/10.1016/0304-3835(83)90055-1
Publication status	Published - 1983

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title = "PYROLYTIC PRODUCTS FROM TRYPTOPHAN AND GLUTAMIC-ACID ARE POSITIVE IN THE MAMMALIAN SPOT-TEST",

abstract = "Pyrolysates of tryptophan (Trp-P-2) and glutamic acid (Glu-P-1) are known mutagens in in vitro short term mutagenicity tests, and have also shown carcinogenic effects in long term animal studies. The present study demonstrates that they also produce mutations in somatic cells. This result demonstrates the ability of the test to detect carcinogenic and mutagenic compounds.",

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AU - Jensen, Niels Juul

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N2 - Pyrolysates of tryptophan (Trp-P-2) and glutamic acid (Glu-P-1) are known mutagens in in vitro short term mutagenicity tests, and have also shown carcinogenic effects in long term animal studies. The present study demonstrates that they also produce mutations in somatic cells. This result demonstrates the ability of the test to detect carcinogenic and mutagenic compounds.

AB - Pyrolysates of tryptophan (Trp-P-2) and glutamic acid (Glu-P-1) are known mutagens in in vitro short term mutagenicity tests, and have also shown carcinogenic effects in long term animal studies. The present study demonstrates that they also produce mutations in somatic cells. This result demonstrates the ability of the test to detect carcinogenic and mutagenic compounds.

U2 - 10.1016/0304-3835(83)90055-1

DO - 10.1016/0304-3835(83)90055-1

M3 - Journal article

SN - 0304-3835

VL - 20

SP - 241

EP - 244

JO - Cancer Letters

JF - Cancer Letters

IS - 2

ER -

PYROLYTIC PRODUCTS FROM TRYPTOPHAN AND GLUTAMIC-ACID ARE POSITIVE IN THE MAMMALIAN SPOT-TEST

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