PYROLYTIC PRODUCTS FROM TRYPTOPHAN AND GLUTAMIC-ACID ARE POSITIVE IN THE MAMMALIAN SPOT-TEST

Niels Juul Jensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Pyrolysates of tryptophan (Trp-P-2) and glutamic acid (Glu-P-1) are known mutagens in in vitro short term mutagenicity tests, and have also shown carcinogenic effects in long term animal studies. The present study demonstrates that they also produce mutations in somatic cells. This result demonstrates the ability of the test to detect carcinogenic and mutagenic compounds.
Original languageEnglish
JournalCancer Letters
Volume20
Issue number2
Pages (from-to)241-244
ISSN0304-3835
DOIs
Publication statusPublished - 1983

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