Pyrolytic carbon microelectrodes for impedance based cell sensing

Yasmin Mohamed Hassan, Claudia Caviglia, Suhith Hemanth, David Mackenzie, Dirch Hjorth Petersen, Stephan Sylvest Keller

    Research output: Contribution to journalConference articleResearchpeer-review

    Abstract

    Electrically conductive glass-like carbon structures can be obtained from a polymer template through a pyrolysis process. These structures can be used as electrodes for bio sensing applications such as electrochemical evaluation of cell adhesion and proliferation. This study focuses on the optimization of two dimensional (2D) pyrolytic carbon microelectrodes with the carbon MEMS (C-MEMS) process using the negative epoxy photoresist SU-8. Different electrochemical microchips with carbon working (WE) and counter electrode (CE) were fabricated. More specifically, pyrolysis process was optimized to decrease the resistivity of the resulting carbon material and improve the performance in cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Finally, EIS was used to monitor adhesion and proliferation of HeLa cells.
    Original languageEnglish
    JournalE C S Transactions
    Volume72
    Issue number1
    Pages (from-to)35-44
    ISSN1938-5862
    DOIs
    Publication statusPublished - 2016
    EventThe 229th ECS Meeting - San Diego, CA, United States
    Duration: 29 May 20162 Jun 2016
    Conference number: 229
    http://www.electrochem.org/229

    Conference

    ConferenceThe 229th ECS Meeting
    Number229
    CountryUnited States
    CitySan Diego, CA
    Period29/05/201602/06/2016
    Internet address

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