Pulse Radiolysis of Adrenaline in Acid Aqueous Solutions

M. Gohn, N. Getoff, Erling Bjergbakke

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Pulse radiolysis of adrenaline in acid aqueous solutions (pH 1–3) was carried out. The rate constants for the reactions of adrenaline with H and OH were determined: k(H + adr.) = (0·9±0·1) × 109 dm3 mol−1s−1; k(OH + adr.) = (1·65±0·15) × 1010 dm3 mol−1s−1. The H-adduct of adrenaline has two λmax, at 280 and 355 nm, with ϵ280 = 420 m2 mol−1 and ϵ355 = 390 m2 mol−1, which disappears according to a first order reaction, k1 = 1·4 × 103 s−1. The spectra formed by OH attack was assigned to the corresponding benzoxy radical with absorption maxima at 285 and 365 nm and ϵ285 = 620 m2 mol−1 and ϵ365 = 105 m2 mol−1. Due to the overlapping of the intermediates, no decay kinetics could be obtained.
    Original languageEnglish
    JournalInternational Journal for Radiation Physics and Chemistry
    Volume8
    Issue number5
    Pages (from-to)533-538
    ISSN0020-7055
    DOIs
    Publication statusPublished - 1976

    Cite this

    Gohn, M. ; Getoff, N. ; Bjergbakke, Erling. / Pulse Radiolysis of Adrenaline in Acid Aqueous Solutions. In: International Journal for Radiation Physics and Chemistry. 1976 ; Vol. 8, No. 5. pp. 533-538.
    @article{109f981f3c0c49fdbd0445839130b117,
    title = "Pulse Radiolysis of Adrenaline in Acid Aqueous Solutions",
    abstract = "Pulse radiolysis of adrenaline in acid aqueous solutions (pH 1–3) was carried out. The rate constants for the reactions of adrenaline with H and OH were determined: k(H + adr.) = (0·9±0·1) × 109 dm3 mol−1s−1; k(OH + adr.) = (1·65±0·15) × 1010 dm3 mol−1s−1. The H-adduct of adrenaline has two λmax, at 280 and 355 nm, with ϵ280 = 420 m2 mol−1 and ϵ355 = 390 m2 mol−1, which disappears according to a first order reaction, k1 = 1·4 × 103 s−1. The spectra formed by OH attack was assigned to the corresponding benzoxy radical with absorption maxima at 285 and 365 nm and ϵ285 = 620 m2 mol−1 and ϵ365 = 105 m2 mol−1. Due to the overlapping of the intermediates, no decay kinetics could be obtained.",
    author = "M. Gohn and N. Getoff and Erling Bjergbakke",
    year = "1976",
    doi = "10.1016/0020-7055(76)90019-X",
    language = "English",
    volume = "8",
    pages = "533--538",
    journal = "International Journal for Radiation Physics and Chemistry",
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    Pulse Radiolysis of Adrenaline in Acid Aqueous Solutions. / Gohn, M.; Getoff, N.; Bjergbakke, Erling.

    In: International Journal for Radiation Physics and Chemistry, Vol. 8, No. 5, 1976, p. 533-538.

    Research output: Contribution to journalJournal articleResearchpeer-review

    TY - JOUR

    T1 - Pulse Radiolysis of Adrenaline in Acid Aqueous Solutions

    AU - Gohn, M.

    AU - Getoff, N.

    AU - Bjergbakke, Erling

    PY - 1976

    Y1 - 1976

    N2 - Pulse radiolysis of adrenaline in acid aqueous solutions (pH 1–3) was carried out. The rate constants for the reactions of adrenaline with H and OH were determined: k(H + adr.) = (0·9±0·1) × 109 dm3 mol−1s−1; k(OH + adr.) = (1·65±0·15) × 1010 dm3 mol−1s−1. The H-adduct of adrenaline has two λmax, at 280 and 355 nm, with ϵ280 = 420 m2 mol−1 and ϵ355 = 390 m2 mol−1, which disappears according to a first order reaction, k1 = 1·4 × 103 s−1. The spectra formed by OH attack was assigned to the corresponding benzoxy radical with absorption maxima at 285 and 365 nm and ϵ285 = 620 m2 mol−1 and ϵ365 = 105 m2 mol−1. Due to the overlapping of the intermediates, no decay kinetics could be obtained.

    AB - Pulse radiolysis of adrenaline in acid aqueous solutions (pH 1–3) was carried out. The rate constants for the reactions of adrenaline with H and OH were determined: k(H + adr.) = (0·9±0·1) × 109 dm3 mol−1s−1; k(OH + adr.) = (1·65±0·15) × 1010 dm3 mol−1s−1. The H-adduct of adrenaline has two λmax, at 280 and 355 nm, with ϵ280 = 420 m2 mol−1 and ϵ355 = 390 m2 mol−1, which disappears according to a first order reaction, k1 = 1·4 × 103 s−1. The spectra formed by OH attack was assigned to the corresponding benzoxy radical with absorption maxima at 285 and 365 nm and ϵ285 = 620 m2 mol−1 and ϵ365 = 105 m2 mol−1. Due to the overlapping of the intermediates, no decay kinetics could be obtained.

    U2 - 10.1016/0020-7055(76)90019-X

    DO - 10.1016/0020-7055(76)90019-X

    M3 - Journal article

    VL - 8

    SP - 533

    EP - 538

    JO - International Journal for Radiation Physics and Chemistry

    JF - International Journal for Radiation Physics and Chemistry

    SN - 0020-7055

    IS - 5

    ER -