@inproceedings{a50f5d047b6c49f48a0719e006bd9fe7,
title = "PSE opportunities in biocatalytic process design and development",
abstract = "Biocatalysis (the use of one or more isolated enzymes in soluble or immobilized form, as well as enzymes contained within resting whole-cells) is a rapidly growing area of process technology. The introduction of biocatalysis presents new opportunities to develop {\textquoteleft}green{\textquoteright} synthetic routes to pharmaceuticals and other chemical products, since enzymes usually work in an aqueous solution and under mild conditions. Nevertheless the implementation of a biocatalytic reaction and the integration of a biocatalytic reaction into an otherwise chemical catalytic sequence is a complex task where PSE tools have a particularly important role to play. In this paper we will present a variety of PSE tools including computational fluid dynamics (CFD), operating windows, kinetic modelling, economic analysis and environmental assessment to support the development of economically viable biocatalytic processes.",
keywords = "Process template, Substrate adoption, Methodology, Pharmaceutical",
author = "P{\"a}r Tufvesson and Ulrich Kr{\"u}hne and Krist Gernaey and John Woodley",
note = "Oral presentation.; 11th International Symposium on Process Systems Engineering, PSE-2012 ; Conference date: 15-07-2012 Through 19-07-2012",
year = "2012",
language = "English",
series = "Computer Aided Chemical Engineering",
publisher = "Elsevier",
pages = "875--879",
editor = "I.A. Karimi and Rajagopalan Srinivasa",
booktitle = "Proceedings of the 11th International Symposium on Process Systems Engineering",
address = "United Kingdom",
}